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KMID : 0357919810150020166
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Korean Journal of Pathology
1981 Volume.15 No. 2 p.166 ~ p.170
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Gastric and Retroperitoneal Epithelioid Leiomyosarcoima(light and electron microscopic observations)
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Abstract
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Two cases of epithelioid leiomyosarcomas are presented. Recently epithelioid
leiomyosarcomas are distinguished from the benign epithelioid leiomyosarcomas. Both
benign and malignant forms of epithelioid smooth muscle tumor have been designated as
leiomyoblastomas which were noncommittal term in implying either benignity or
malignancy.
The one of our cases was gastric epithelioid leiomyosarcoma and the other was
epithelioid leiomyosarcoma of the retroperitoneum. They were composed of a mixture of
round epithelioid and spindle cells, which have clear cytoplasm in many cells.
The gastric epithelioid leiomyosarcoma had more than five mitoses/10 HPF, areas of
compact hypercellularty of small size and 15cm in maximum diameter of the mass.
Although the retropfritoneal tumor had infrequent mitoses, the tumor showed extensive
necrosis and 20cm in largest diameter. These findings were considered as strongly
suggestive findings of malignancy at the site of retroperitoneum.
Ultrastructural findings of both tumors were some amounts of rough endoplasmic
reticulum, vacuoles of varying size, fibrillar structures in the cytoplasm, and occasionally
basement membrane-like structure at the cell junctions.
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KEYWORD
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